Early-Onset Posterior Subcapsular Cataract is related to early-onset posterior polar cataract and aniridia 1. An important gene associated with Early-Onset Posterior Subcapsular Cataract is CHMP4B (Charged Multivesicular Body Protein 4B), and among its related pathways/superpathways is Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding. Affiliated tissues include eye.