Erdheim-Chester Disease

Alias:

Polyostotic Sclerosing Histiocytosis

Lipid Granulomatosis

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Erdheim-Chester Disease, also known as polyostotic sclerosing histiocytosis, is related to histiocytosis and exanthem. An important gene associated with Erdheim-Chester Disease is BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways/superpathways are Signal Transduction and ERK Signaling. The drugs Vemurafenib and Lenalidomide have been mentioned in the context of this disorder. Affiliated tissues include bone and skin, and related phenotypes are hyperhidrosis and polydipsia

Related ID：

MALACARDS：ERD001

MESH：D031249