Epidermolysis Bullosa Simplex 2a, Generalized Severe (EBS2A)

Epidermolysis Bullosa Simplex 2a, Generalized Severe, also known as epidermolysis bullosa simplex 2a, dowling-meara type, is related to epidermolysis bullosa simplex and epidermolysis bullosa simplex 2e, with migratory circinate erythema. An important gene associated with Epidermolysis Bullosa Simplex 2a, Generalized Severe is KRT5 (Keratin 5). Affiliated tissues include skin, and related phenotypes are abnormal blistering of the skin and oral mucosal blisters