Epidermolysis Bullosa Dystrophica, Autosomal Dominant (DDEB)

Epidermolysis Bullosa Dystrophica, Autosomal Dominant, also known as autosomal dominant dystrophic epidermolysis bullosa, is related to glomerulonephritis and epidermolysis bullosa. An important gene associated with Epidermolysis Bullosa Dystrophica, Autosomal Dominant is COL7A1 (Collagen Type VII Alpha 1 Chain), and among its related pathways/superpathways are Complement cascade and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). Affiliated tissues include skin and liver, and related phenotypes are abnormal blistering of the skin and sub-lamina densa cleavage