Epidermolysis Bullosa Simplex Superficialis, also known as ebss, is related to transient bullous dermolysis of the newborn and epidermolysis bullosa dystrophica, autosomal dominant. An important gene associated with Epidermolysis Bullosa Simplex Superficialis is COL7A1 (Collagen Type VII Alpha 1 Chain). Affiliated tissues include skeletal muscle and pancreatic islet.