Epidemic Typhus, also known as typhus, is related to siberian tick typhus and indian tick typhus, and has symptoms including high fever, cough and rash. An important gene associated with Epidemic Typhus is AFF2 (ALF Transcription Elongation Factor 2). The drugs Telithromycin and Doxycycline have been mentioned in the context of this disorder. Affiliated tissues include endothelial and t cells.