Enamel Caries, also known as primary dental caries, is related to dental caries and dentin caries. An important gene associated with Enamel Caries is CA10 (Carbonic Anhydrase 10), and among its related pathways/superpathways is Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). The drugs Salicylic acid and Chlorhexidine have been mentioned in the context of this disorder.