Endometrial Serous Adenocarcinoma

Endometrial Serous Adenocarcinoma, also known as uterine serous carcinoma, is related to papillary serous adenocarcinoma and ovarian serous carcinoma. An important gene associated with Endometrial Serous Adenocarcinoma is ATM (ATM Serine/Threonine Kinase), and among its related pathways/superpathways are Prolactin Signaling and Regulation of TP53 Activity. The drugs Letrozole and Everolimus have been mentioned in the context of this disorder. Affiliated tissues include uterus and lymph node, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Synthetic lethal with MLN4924 (a NAE inhibitor)