Endocrine System Disease, also known as abnormality of the endocrine system, is related to pancreas disease and thyroid gland disease, and has symptoms including pathological conditions, signs and symptoms, breast pain male and cushingoid facies. An important gene associated with Endocrine System Disease is MIR199A1 (MicroRNA 199a-1), and among its related pathways/superpathways are miRNAs involved in DNA damage response and miRNA role in immune response in sepsis. The drugs Zinc cation and Hydrocortisone have been mentioned in the context of this disorder. Affiliated tissues include brain and bone.