Endosteal Hyperostosis, Autosomal Dominant (WENHY)

Alias:

Worth Syndrome

Worth Disease

Autosomal Dominant Endosteal Hyperostosis

Osteosclerosis, Autosomal Dominant

Hyperostosis, Endosteal

Hyperostosis Corticalis Generalisata, Benign Form of Worth, with Torus Palatinus

Hyperostosis Corticalis Generalisata Benign Form of Worth with Torus Palatinus

Benign Form of Worth Hyperostosis Corticalis Generalisata with Torus Platinus

Endosteal Hyperostosis Autosomal Dominant

Endosteal Hyperostosis, Worth Type

Autosomal Dominant Osteosclerosis

Osteosclerosis Autosomal Dominant

Endosteal Hyperostosis

Worth's Syndrome

Osteosclerosis

Wenhy

Favorite

Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Endosteal Hyperostosis, Autosomal Dominant, also known as worth syndrome, is related to van buchem disease and hyperostosis. An important gene associated with Endosteal Hyperostosis, Autosomal Dominant is LRP5 (LDL Receptor Related Protein 5), and among its related pathways/superpathways are Ion channel transport and Clock-controlled autophagy in bone metabolism. The drugs Soy Bean and Salicylic acid have been mentioned in the context of this disorder. Affiliated tissues include bone and cortex, and related phenotypes are dental malocclusion and sensorineural hearing impairment

Related ID：

MALACARDS：END081

OMIM：144750

MESH：C536748