Endemic Goiter

Endemic Goiter, also known as iodine-deficiency-related endemic goitre, is related to goiter, multinodular 1, with or without sertoli-leydig cell tumors and hypothyroidism, congenital, nongoitrous, 2. An important gene associated with Endemic Goiter is TPO (Thyroid Peroxidase), and among its related pathways/superpathways are Regulation of expression of SLITs and ROBOs and G alpha (s) signalling events. The drugs Methimazole and Hormone Antagonists have been mentioned in the context of this disorder. Affiliated tissues include thyroid and pituitary, and related phenotypes are Increased HPV16-GFP infection and growth/size/body region