Encephalopathy, Acute, Infection-Induced 6, is also known as herpes simplex encephalitis, susceptibility to, 4. An important gene associated with Encephalopathy, Acute, Infection-Induced 6 is TICAM1 (TIR Domain Containing Adaptor Molecule 1). Related phenotypes are herpes simplex encephalitis and recurrent aphthous stomatitis