Elephantiasis is related to podoconiosis and loiasis. An important gene associated with Elephantiasis is ELANE (Elastase, Neutrophil Expressed), and among its related pathways/superpathways are ERK Signaling and PAK Pathway. The drugs Glycerin and Petrolatum have been mentioned in the context of this disorder. Affiliated tissues include skin and liver, and related phenotype is digestive/alimentary.