Ectrodactyly and Ectodermal Dysplasia Without Cleft Lip/palate, is also known as eec syndrome without cleft lip/palate. An important gene associated with Ectrodactyly and Ectodermal Dysplasia Without Cleft Lip/palate is LEF1 (Lymphoid Enhancer Binding Factor 1). Affiliated tissues include kidney and skin.