Dystonia 12 (DYT12)

Dystonia 12, also known as dyt12, is related to leber optic atrophy and dystonia and dystonia 3, torsion, x-linked, and has symptoms including dystonia, myoclonus and torticollis. An important gene associated with Dystonia 12 is ATP1A3 (ATPase Na+/K+ Transporting Subunit Alpha 3), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Ion channel transport. The drugs Acetylcholine and Cholinergic Agents have been mentioned in the context of this disorder. Affiliated tissues include globus pallidus and subthalamic nucleus, and related phenotypes are dysarthria and dysphagia