Dysostosis

Dysostosis, also known as dysostoses, is related to mandibulofacial dysostosis, guion-almeida type and acrofacial dysostosis 1, nager type. An important gene associated with Dysostosis is DLL3 (Delta Like Canonical Notch Ligand 3), and among its related pathways/superpathways are Gastrulation and Neural crest differentiation. The drugs Cimetidine and Calcium, Dietary have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotypes are growth/size/body region and nervous system