Dextrocardia

Dextrocardia, also known as heart predominantly in right hemithorax, is related to ciliary dyskinesia, primary, 1 and total anomalous pulmonary venous return 1. An important gene associated with Dextrocardia is CFAP53 (Cilia And Flagella Associated Protein 53), and among its related pathways/superpathways are Beta-2 adrenergic-dependent CFTR expression and Human Embryonic Stem Cell Pluripotency. The drugs Spironolactone and Mineralocorticoid Receptor Antagonists have been mentioned in the context of this disorder. Affiliated tissues include heart and lung, and related phenotypes are dextrocardia and abnormal heart morphology