Dowling-Degos Disease 1 (DDD1)

Dowling-Degos Disease 1, also known as reticular pigment anomaly of flexures, is related to microphthalmia and pheochromocytoma. An important gene associated with Dowling-Degos Disease 1 is KRT5 (Keratin 5), and among its related pathways/superpathways are Infectious disease and Signal Transduction. The drugs Clindamycin and Desonide have been mentioned in the context of this disorder. Affiliated tissues include skin and breast, and related phenotypes are growth/size/body region and nervous system