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ENDowling-Degos Disease (DDD)
Alias:
Reticular Pigment Anomaly of Flexures
Dark Dot Disease
Reticulate Acropigmentation of Kitamura
Reticular Pigmented Anomaly of Flexures
Dowling-Degos-Kitamura Disease
Ddd
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Dowling-Degos Disease, also known as reticular pigment anomaly of flexures, is related to reticulate acropigmentation of kitamura and anal canal squamous cell carcinoma. An important gene associated with Dowling-Degos Disease is POFUT1 (Protein O-Fucosyltransferase 1), and among its related pathways/superpathways are Signal Transduction and O-linked glycosylation of mucins. Affiliated tissues include skin and liver, and related phenotypes are progressive reticulate hyperpigmentation and hyperkeratosis
Related ID：
MESH：C562924
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MALACARDS
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