Developmental and Epileptic Encephalopathy 4, also known as epileptic encephalopathy, early infantile, 4, is related to early infantile epileptic encephalopathy and infantile epilepsy syndrome, and has symptoms including muscle spasticity, tremor and tonic seizures. An important gene associated with Developmental and Epileptic Encephalopathy 4 is STXBP1 (Syntaxin Binding Protein 1). The drugs Fenfluramine and Stiripentol have been mentioned in the context of this disorder. Affiliated tissues include brain, and related phenotypes are intellectual disability, profound and eeg with burst suppression