Disorder of Sexual Development

Disorder of Sexual Development, also known as disorders of sex development, is related to mullerian aplasia and hyperandrogenism and gonadal dysgenesis. An important gene associated with Disorder of Sexual Development is DMRT1 (Doublesex And Mab-3 Related Transcription Factor 1), and among its related pathways/superpathways are Signal Transduction and Nervous system development. The drugs Methyltestosterone and Testosterone have been mentioned in the context of this disorder. Affiliated tissues include uterus and testis, and related phenotypes are Increased shRNA abundance (Z-score > 2) and endocrine/exocrine gland