Desmoplastic/nodular Medulloblastoma (MBEN)

Desmoplastic/nodular Medulloblastoma, also known as medulloblastoma with extensive nodularity, is related to basal cell carcinoma 1 and rhabdoid cancer, and has symptoms including headache, vomiting and gait ataxia. An important gene associated with Desmoplastic/nodular Medulloblastoma is SUFU (SUFU Negative Regulator Of Hedgehog Signaling), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Picropodophyllin and Vincristine have been mentioned in the context of this disorder. Affiliated tissues include cerebellum and brain, and related phenotypes are Increased shRNA abundance (Z-score > 2) and shRNA abundance <= 50%