Desmoid Disease, Hereditary (DESMD)

Desmoid Disease, Hereditary, also known as fif, is related to desmoid tumor and familial adenomatous polyposis 1. An important gene associated with Desmoid Disease, Hereditary is APC (APC Regulator Of WNT Signaling Pathway), and among its related pathways/superpathways are Presenilin action in Notch and Wnt signaling and Deactivation of the beta-catenin transactivating complex. The drugs Sorafenib and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include breast and colon, and related phenotypes are desmoid tumors and colorectal polyposis