Diarrhea 2, with Microvillus Atrophy, with or Without Cholestasis, also known as congenital familial protracted diarrhea with enterocyte brush-border abnormalities, is related to microvillus inclusion disease and diarrhea 11, malabsorptive, congenital. An important gene associated with Diarrhea 2, with Microvillus Atrophy, with or Without Cholestasis is MYO5B (Myosin VB). Affiliated tissues include breast and lung, and related phenotypes are protracted diarrhea and dehydration