Dermatofibrosarcoma Protuberans (DFSP)

Dermatofibrosarcoma Protuberans, also known as dermatofibrosarcoma, is related to myxofibrosarcoma and skin sarcoma. An important gene associated with Dermatofibrosarcoma Protuberans is PDGFB (Platelet Derived Growth Factor Subunit B), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Signaling by Receptor Tyrosine Kinases. The drugs Ifosfamide and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include skin and breast, and related phenotypes are subcutaneous nodule and neoplasm of the skin