Dupuytren Contracture

Alias:
Dupuytren Contracture 1
Palmar Fascial Fibromatosis
Dupuytren's Contracture
Dupuytren's Contraction or Disease
Contraction of Palmar Fascia
Familial Palmar Fibromatosis
Contracture of Palmar Fascia
Retraction of Palmar Fascia
Dupuytren Disease of Palm
Palmar Fibromatosis
Dupuytren Disease
Palmar Fibromas
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Dupuytren Contracture, also known as palmar fascial fibromatosis, is related to plantar fascial fibromatosis and ledderhose disease. An important gene associated with Dupuytren Contracture is DUPC1 (Dupuytren Contracture 1), and among its related pathways/superpathways are NF-KappaB Family Pathway and G-protein signaling RAC1 in cellular process. The drugs Tranexamic acid and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include skin and liver, and related phenotypes are joint contracture of the hand and dupuytren contracture
Related ID:

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Unknown
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2
17
15

Medical Symptom

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Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Related Drugs

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No data available

Disease Model

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MGI
Related Gene
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Publications
No data available

References Literature

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