Dent Disease 2 (DENT2)

Dent Disease 2, also known as dent disease type 2, is related to dent disease 1 and lowe oculocerebrorenal syndrome. An important gene associated with Dent Disease 2 is OCRL (OCRL Inositol Polyphosphate-5-Phosphatase), and among its related pathways/superpathways are Inositol phosphate metabolism and superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism. Affiliated tissues include kidney and bone, and related phenotypes are umbilical hernia and hypercalciuria