Dentinogenesis Imperfecta (DI)

Alias:
Hereditary Opalescent Dentin
Dentinogenesis Imperfecta Without Osteogenesis Imperfecta
Dgi
Opalescent Teeth Without Osteogenesis Imperfecta
Non-Syndromic Dentinogenesis Imperfecta
Opalescent Teeth Without Oi
Non-Syndromic Dgi
Dgi Without Oi
Di
Opalescent Dentin
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Dentinogenesis Imperfecta, also known as hereditary opalescent dentin, is related to dentinogenesis imperfecta 1 and osteogenesis imperfecta, type vii. An important gene associated with Dentinogenesis Imperfecta is DSPP (Dentin Sialophosphoprotein), and among its related pathways/superpathways are Phospholipase-C Pathway and PI3K-Akt signaling pathway. Affiliated tissues include Tooth, bone and skin, and related phenotypes are pulp obliteration and abnormal dental root morphology
Related ID:
MESH:D003811
ICD11:2090257992

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Child
1-5/10000
34
455
8

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
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