Dentatorubral-Pallidoluysian Atrophy (DRPLA)

Dentatorubral-Pallidoluysian Atrophy, also known as drpla, is related to progressive myoclonus epilepsy and choreatic disease, and has symptoms including cerebellar ataxia, myoclonus and seizures. An important gene associated with Dentatorubral-Pallidoluysian Atrophy is ATN1 (Atrophin 1), and among its related pathways/superpathways are Akt Signaling and Neuroscience. The drugs Dopamine and Ropinirole have been mentioned in the context of this disorder. Affiliated tissues include brain and globus pallidus, and related phenotypes are progressive cerebellar ataxia and atrophy of the dentate nucleus