Dengue Disease, also known as dengue fever, is related to dengue hemorrhagic fever and dengue shock syndrome, and has symptoms including fever and pruritus. An important gene associated with Dengue Disease is NEAT1 (Nuclear Paraspeckle Assembly Transcript 1), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. The drugs Ketotifen and Histamine have been mentioned in the context of this disorder. Affiliated tissues include skin and liver, and related phenotypes are fever and headache