Danubian Endemic Familial Nephropathy (BEN)

Danubian Endemic Familial Nephropathy, also known as balkan nephropathy, is related to hantavirus hemorrhagic fever with renal syndrome and anuria, and has symptoms including headache, nausea and back pain. An important gene associated with Danubian Endemic Familial Nephropathy is B2M (Beta-2-Microglobulin), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drug Antibodies has been mentioned in the context of this disorder. Affiliated tissues include kidney and skin, and related phenotypes are nephropathy and Synthetic lethal with MLN4924 (a NAE inhibitor)