Degenerative Disc Disease, also known as intervertebral disc degeneration, is related to back pain and spinal stenosis, and has symptoms including sciatica An important gene associated with Degenerative Disc Disease is LINC01562 (Long Intergenic Non-Protein Coding RNA 1562), and among its related pathways/superpathways are Extracellular matrix organization and Endochondral ossification with skeletal dysplasias. The drugs Morphine and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include Cartilage, bone and bone marrow.