Difference of Sex Development (DSD)

Difference of Sex Development, also known as disorder of sex development, is related to 17-beta hydroxysteroid dehydrogenase iii deficiency and adrenal insufficiency, congenital, with 46,xy sex reversal, partial or complete. An important gene associated with Difference of Sex Development is HSD17B3 (Hydroxysteroid 17-Beta Dehydrogenase 3), and among its related pathways/superpathways is Mammalian disorder of sexual development. The drugs Methyltestosterone and Testosterone have been mentioned in the context of this disorder. Affiliated tissues include testis and brain, and related phenotypes are Increased shRNA abundance (Z-score > 2) and nervous system