Diffuse Gastric Cancer

Diffuse Gastric Cancer, also known as gastric signet ring carcinoma, is related to diffuse gastric and lobular breast cancer syndrome and gastric adenocarcinoma. An important gene associated with Diffuse Gastric Cancer is CDH1 (Cadherin 1), and among its related pathways/superpathways are Infectious disease and Formation of HIV elongation complex in the absence of HIV Tat. The drugs Irinotecan and Bevacizumab have been mentioned in the context of this disorder. Affiliated tissues include prostate and breast, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Decreased viability after ionizing radiation