Dacryocystocele, also known as lacrimal mucocele, is related to pleural empyema and diaphragmatic hernia, congenital. An important gene associated with Dacryocystocele is FREM2 (FRAS1 Related Extracellular Matrix 2), and among its related pathways/superpathways are ERK Signaling and PAK Pathway. The drug Mitomycins has been mentioned in the context of this disorder. Affiliated tissues include smooth muscle and eye, and related phenotypes are Increased shRNA abundance (Z-score > 2) and cellular