Diabetes Insipidus, Nephrogenic, 1, X-Linked, also known as ndi1, is related to diabetes insipidus, nephrogenic, with mental retardation and intracerebral calcification and nephrogenic diabetes insipidus. An important gene associated with Diabetes Insipidus, Nephrogenic, 1, X-Linked is AVPR2 (Arginine Vasopressin Receptor 2). The drugs Amiloride and diuretics have been mentioned in the context of this disorder. Affiliated tissues include kidney and liver.