Diabetic Encephalopathy is related to diabetic neuropathy and hyperglycemia. An important gene associated with Diabetic Encephalopathy is INS (Insulin), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. Affiliated tissues include brain and cortex, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and homeostasis/metabolism