Diabetes Mellitus, Neonatal, with Congenital Hypothyroidism, also known as neonatal diabetes mellitus with congenital hypothyroidism, is related to neonatal diabetes and congenital hypothyroidism. An important gene associated with Diabetes Mellitus, Neonatal, with Congenital Hypothyroidism is GLIS3 (GLIS Family Zinc Finger 3), and among its related pathways/superpathways are Thyroid hormones production and peripheral downstream signaling effects and Metabolism of amine-derived hormones. Affiliated tissues include thyroid and kidney, and related phenotypes are osteopenia and splenomegaly