Cayler Cardiofacial Syndrome (ACF)

Cayler Cardiofacial Syndrome, also known as asymmetric crying facies, is related to chromosome 22q11.2 deletion syndrome, distal and congenital unilateral hypoplasia of depressor anguli oris. An important gene associated with Cayler Cardiofacial Syndrome is ACF (Asymmetric Crying Facies (Cayler Cardiofacial Syndrome)). Affiliated tissues include heart and eye, and related phenotypes are tetralogy of fallot and patent ductus arteriosus