Cowden Syndrome 4 (CWS4)

Cowden Syndrome 4, also known as cws4, is related to gangliocytoma and nodular malignant melanoma. An important gene associated with Cowden Syndrome 4 is KLLN (Killin, P53 Regulated DNA Replication Inhibitor), and among its related pathways/superpathways are Endometrial cancer and p53 transcriptional gene network. Affiliated tissues include thyroid and breast, and related phenotypes are macrocephaly and breast carcinoma