Castleman Disease, also known as angiofollicular ganglionic hyperplasia, is related to multicentric castleman disease and kaposi sarcoma. An important gene associated with Castleman Disease is IL6 (Interleukin 6), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Dexamethasone and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include lymph node and spleen, and related phenotypes are lymphadenopathy and fatigue