Crouzon Syndrome with Acanthosis Nigricans (CAN)

Crouzon Syndrome with Acanthosis Nigricans, also known as crouzon syndrome-acanthosis nigricans syndrome, is related to acanthosis nigricans and luteoma. An important gene associated with Crouzon Syndrome with Acanthosis Nigricans is FGFR3 (Fibroblast Growth Factor Receptor 3), and among its related pathways/superpathways are Breast cancer pathway and MAPK signaling pathway. Affiliated tissues include eye and skin, and related phenotypes are frontal bossing and high forehead