Cryptophthalmos, Unilateral or Bilateral, Isolated (CRYPTOP)

Cryptophthalmos, Unilateral or Bilateral, Isolated, also known as isolated cryptophthalmia, is related to congenital symblepharon and partial cryptophthalmia. An important gene associated with Cryptophthalmos, Unilateral or Bilateral, Isolated is FREM2 (FRAS1 Related Extracellular Matrix 2), and among its related pathways/superpathways are Phospholipase-C Pathway and Development of ureteric collection system. Affiliated tissues include eye and skin, and related phenotypes are glaucoma and microphthalmia