Cryptococcosis, also known as cryptococcus neoformans infection, is related to meningitis and acquired immunodeficiency syndrome. An important gene associated with Cryptococcosis is IFNG (Interferon Gamma), and among its related pathways/superpathways are Innate Immune System and Complement cascade. The drugs Voriconazole and Cytochrome P-450 CYP3A Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include brain and skin, and related phenotypes are fever and immunodeficiency