Cryoglobulinemia, also known as cryoimmunoglobulinaemia, is related to cryoglobulinemic vasculitis and mononeuritis multiplex. An important gene associated with Cryoglobulinemia is IFNA1 (Interferon Alpha 1), and among its related pathways/superpathways are TGF-Beta Pathway and MIF Mediated Glucocorticoid Regulation. The drugs Sofosbuvir and Velpatasvir have been mentioned in the context of this disorder. Affiliated tissues include liver and b cells, and related phenotypes are immune system and cellular