Carotid Artery Disease, also known as disorder of carotid artery, is related to transient cerebral ischemia and arteries, anomalies of, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Carotid Artery Disease is SLC39A2 (Solute Carrier Family 39 Member 2), and among its related pathways/superpathways are Plasma lipoprotein assembly, remodeling, and clearance and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). The drugs Exenatide and Evolocumab have been mentioned in the context of this disorder. Affiliated tissues include brain and heart, and related phenotypes are Increased free cholesterol and homeostasis/metabolism