Cornelia De Lange Syndrome 3 with or Without Midline Brain Defects (CDLS3)

Cornelia De Lange Syndrome 3 with or Without Midline Brain Defects, also known as cornelia de lange syndrome 3, is related to wiedemann-steiner syndrome and poikiloderma with neutropenia. An important gene associated with Cornelia De Lange Syndrome 3 with or Without Midline Brain Defects is SMC3 (Structural Maintenance Of Chromosomes 3), and among its related pathways/superpathways are 10q22q23 copy number variation and Rett syndrome causing genes. Affiliated tissues include brain and heart, and related phenotypes are intellectual disability and global developmental delay