Corneal Dystrophy, Posterior Polymorphous, 2, also known as posterior polymorphous corneal dystrophy 2, is related to secondary corneal edema and corneal dystrophy, avellino type. An important gene associated with Corneal Dystrophy, Posterior Polymorphous, 2 is COL8A2 (Collagen Type VIII Alpha 2 Chain), and among its related pathways/superpathways is G-protein signaling_Rap2B regulation pathway. Affiliated tissues include endothelial, and related phenotypes are corneal opacity and corneal dystrophy