Corneal Dystrophy, Posterior Polymorphous, 3, also known as posterior polymorphous corneal dystrophy 3, is related to corneal edema and keratoconus. An important gene associated with Corneal Dystrophy, Posterior Polymorphous, 3 is ZEB1 (Zinc Finger E-Box Binding Homeobox 1), and among its related pathways/superpathways are ECM proteoglycans and Epithelial to mesenchymal transition in colorectal cancer. Affiliated tissues include endothelial, and related phenotypes are corneal dystrophy and reduced visual acuity