Crane-Heise Syndrome

Crane-Heise Syndrome, also known as cleft lip/palate, agenesis of clavicles and cervical vertebrae, and talipes equinovarus, is related to spondylocostal dysostosis 1, autosomal recessive and cleft palate, isolated. An important gene associated with Crane-Heise Syndrome is FGD1 (FYVE, RhoGEF And PH Domain Containing 1). Affiliated tissues include bone, and related phenotypes are depressed nasal bridge and hypertelorism